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Company Overview: Dyne Therapeutics is focused on delivering functional improvement for people living with genetically driven neuromuscular diseases. We are developing therapeutics that target muscle and the central nervous system (CNS) to address the root cause of disease. The company is advancing clinical programs for Duchenne muscular dystrophy (DMD) and myotonic dystrophy type 1 (DM1) as well as a preclinical programs for facioscapulohumeral muscular dystrophy (FSHD) and Pompe disease. At Dyne, we are on a mission to deliver functional improvement for individuals, families and communities. Learn more at https://www.dyne-tx.com/ , and follow us on X , LinkedIn  and Facebook . Role Summary: The Vice President, Procurement designs, builds, and leads Dyne’s end-to-end sourcing and procurement function to maximize value from external spend. This role establishes enterprise-wide source-to-pay strategies, policies, and systems, while ensuring alignment with business objectives, regulatory requirements, and operational priorities. The Vice President drives strategic supplier partnerships, oversees complex negotiations, and develops scalable processes to support Dyne’s growth. Additionally, this role provides leadership visibility through reporting, insights, and cross-functional collaboration to enable informed decision-making and sustained organizational impact. This role is based in Waltham, MA. Primary Responsibilities Include: Procurement Strategy & Operations Establish and execute a long-term vision and roadmap for Procurement aligned to Dyne’s strategic objectives Design and implement scalable, end-to-end source-to-pay processes, policies, and governance frameworks Develop and implement a fit-for-purpose operating model, including organizational design and staffing strategy Partner with IT to select, implement, and optimize procurement systems integrated with enterprise platforms Lead procurement compliance activities, including audit readiness and documentation standards Strategic Sourcing & Cross-Functional Partnership Lead complex, high-value sourcing initiatives, including RFP development, supplier evaluation, negotiation, and contracting support Partner closely with Finance, Legal, and functional leaders to ensure alignment with financial, legal, and regulatory requirements Provide strategic guidance, methodology, and governance for enterprise-wide purchasing activities Build strong cross-functional relationships to drive adoption, sponsorship, and adherence to procurement practices Deliver regular reporting and insights on savings, pipeline, risks, and performance against key objectives Supplier Relationship Management Establish and standardize supplier selection, onboarding, and performance management processes Develop and manage strategic supplier relationships, including leading periodic business reviews Monitor supplier performance and drive continuous improvement initiatives Serve as a key liaison between internal stakeholders and external partners to resolve issues and maintain alignment Corporate Social Responsibility & Compliance Establish and advance procurement-related CSR initiatives, including sustainability, supplier diversity, and ethical sourcing Ensure procurement practices align with corporate policies, regulatory requirements, and industry standards Support external reporting requirements and ESG-related disclosures as applicable Education and Skills Requirements: Bachelor’s degree required At least 20+ years purchasing/procurement experience in the biotech/pharma industry Experience with ERP / MRP / Procurement systems, processes and tools is a must Previous experience of working in a global business with matrix management Must be a self-starter and highly organized Excellent planning, interpersonal, and organizational skills Experienced and comfortable leading complex init