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About Beeline Medicines: Beeline Medicines is a clinical‑stage biotechnology company focused on developing and delivering category-leading precision therapies to transform the lives of people living with autoimmune and inflammatory diseases. With a portfolio of potential best-in-class and first-in-disease therapeutic candidates that directly target key pathways governing dysregulated immunological and inflammatory responses, the Company is developing medicines that have the opportunity to provide durable, life-changing impact. Led by an established executive team and backed by world-class life science investors, each day Beeline Medicines is determined to bring the scientific rigor and operational excellence to get to what matters for patients – realizing a world where people with immune-mediated diseases can live life fully. Job Summary: The Staff Accountant is a foundational member of Accounting team, responsible for supporting the day-to-day accounting operations, monthly close process, and financial reporting activities of a clinical-stage biotech. This role provides accurate and timely accounting support across general ledger maintenance, accounts payable, account reconciliations, and expense reporting — contributing to the integrity of the financial records that underpin the organization's reporting and compliance obligations. Operating in a lean finance environment, the Staff Accountant is expected to bring attention to detail, a strong work ethic, and a genuine desire to build foundational accounting skills in a fast-paced, high-growth life sciences setting. This is an excellent opportunity for an early-career accounting professional to gain broad exposure to all aspects of biotech accounting and develop their skills alongside an experienced Finance team. Work Arrangement & Location:  Hybrid - This position follows a hybrid work schedule, requiring a minimum of two (2) days on-site per week — currently designated as Tuesday and Wednesday . Additional on-site days may be required based on business needs, team priorities, or leadership direction. Essential Duties and Responsibilities: Support the monthly financial close process — preparing and posting journal entries, performing account reconciliations, and assisting with the preparation of close workpapers across assigned accounting areas including prepaid expenses, accruals, and fixed assets. Process and manage accounts payable activities — reviewing and coding vendor invoices, coordinating approval workflows, maintaining vendor records, and supporting timely and accurate payment processing in accordance with company policies. Prepare and maintain accounting schedules and supporting documentation for assigned balance sheet accounts — ensuring all reconciliations are completed accurately, on schedule, and supported by appropriate backup documentation. Support clinical and research program accrual processes — working with Clinical Operations, Finance, and external vendors to track program expenditures, estimate accruals, and ensure accurate recording of CRO and research-related costs. Assist in the preparation of external audit support — organizing workpapers, preparing schedules, and gathering documentation in response to auditor requests under the direction of the Manager, Accounting. Support accounts payable vendor management — maintaining accurate vendor master data, processing new vendor setups, and ensuring W-9/W-8 compliance in coordination with Tax and Finance leadership. Contribute to the continuous improvement of accounting processes — identifying opportunities to streamline workflows, improve documentation standards, and enhance the efficiency of close and reporting activities. Perform other duties and responsibilities as assigned Qualifications: Education: Bachelor's degree in Accounting or Finance required. CPA exam eligibility or active progress toward CPA licensur