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Senior Medical Director

Maze Therapeutics
CompanyMaze Therapeutics
CategoryHealthcare
LocationSouth San Francisco
RemoteOn-site (inferred)
EmploymentNot stated
LevelDirector
SalaryNot stated by the employer
Posted1 Jun 2026
Last verified12 Aug 2026
SourceEmployer ATS (greenhouse)
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Description
The Position At Maze Therapeutics, we are assembling a team of passionate, creative, and dedicated professionals to join us on our mission to turn groundbreaking genetic discoveries into life-saving medicines. We're looking for a  Senior Medical Director  to join our Clinical Sciences team and take a central role in pioneering the future of healthcare.   As a  Senior  Medical Director,   you'll  be at the forefront of translating genetic insights into  innovative treatments for patients . Your work will  help drive the clinical development programs  for game-changing  therapies, starting with a  small molecule that targets  SLC6A19  – a  novel therapeutic target for the treatment of  chronic kidney disease  and phenylketonuria .     Maze Therapeutics has an exciting pipeline spanning both rare and common renal, cardiac, and metabolic diseases. In short, you'll play a fundamental part in advancing medical breakthroughs that have the potential to transform many lives.    To succeed in this role, you'll need to thrive in a fast-paced, collaborative environment. As a Senior Medical Director for one or more development programs, you will partner closely with cross-functional team members and other technical experts to design, conduct, and interpret the key clinical studies, including first-in-human and proof-of-concept trials. Your contributions will be highly visible and integral to the success of the Maze team.   This position reports to  the Head of Clinical  Development .   The Impact You’ll Have Lead the design, execution, and analysis of   clinical trials for  the  SLC6A19  program and other  early-stage  clinical   assets at Maze   Author and review clinical-regulatory documents, including protocols and amendments, informed consents, study reports, and SAPs     Prepare and deliver scientific presentations  and other communication materials for internal and external stakeholders, including investigators and other Maze collaborators.   Engage with scientific thought leaders and  patient advocacy groups   to  gain insights to inform clinical development plans and  build awareness and enthusiasm for the Maze pipeline assets .   Partner with Clinical Development Operations to  identify  and select study investigators and sites and  b uild strong professional relationships with study investigators.   Partner with Clinical Development Operations to  identify , select, and oversee vendors and CROs to support program needs .   Develop and integrate  timelines and budgets  for  clinical activities with overall company timelines and goals, in close coordination with project management, CMC, nonclinical development, regulatory affairs, and other stakeholders .   As a Senior Director , we also expect our leaders to demonstrate the following Leadership Competencies: Communication and Influence Builds communication channels across Maze for sharing information.   Influences Senior Management decisions through persuasive arguments.   Respectfully addresses differing opinions leading to support of decisions.   Teamwork and Collaboration Champions partnerships and connections across Maze.   Proactively addresses issues that could result in breakdown of team relationships.   Spotlights team and individual contributions in public forums.   Execution and Results Addresses gaps and leverages strengths to get&nbs