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Encoded Therapeutics is a clinical-stage biotechnology company developing precision genetic medicines to transform the lives of patients with severe neurological disorders. The company’s vector engineering platform enables potent and cell-type-selective regulation of gene expression, allowing for targeted modulation of disease-relevant genes. Encoded is advancing a pipeline of programs across genetic epilepsies and other neurological disorders with significant unmet need. With integrated discovery, development, and manufacturing capabilities, Encoded is positioned to efficiently move programs from concept through the clinic. Encoded is driven by a mission to meaningfully improve the lives of patients and families affected by devastating neurological disorders. For more information, please visit  www.encoded.com . We are seeking a high-caliber Senior Director, FP&A to serve as a strategic architect of our financial roadmap. You will be the primary bridge between clinical innovation and financial sustainability. Not only will you manage the numbers but also synthesize complex data into actionable insights for the Leadership Team and Board of Directors, directly influencing the company’s overall business strategy and clinical program investments. This role is based in South San Francisco and reports to the Vice President, Finance. Responsibilities: Strategic Financial Planning: Lead end-to-end annual operating plan, quarterly forecasting (Latest Estimate), Long Range Plan and Scenario Planning processes. Conduct rigorous sensitivity and risk analyses to guide executive decision-making. Establish Commercial Planning process, including P&L modeling, demand planning and competitive analysis. R&D CMC Business Partnership: Act as the dedicated finance lead for R&D and Manufacturing functions. Collaborate on complex clinical study accruals and build robust modeling frameworks to track program-level performance against budgets. Corporate Dashboards & KPIs: Develop and maintain corporate dashboards to track performance against key clinical, program, and operational milestones. Infrastructure Scaling: Build out the FP&A team’s infrastructure to enable flexible forecast modeling, streamlined management reporting, cash forecasting and clinical trial study analytics and reporting Corporate Development Support: Provide financial modeling and due diligence support for M&A, licensing, and clinical investment decisions Cross-Functional Stewardship: Serve as the financial gatekeeper for contract requests via Coupa and act as the primary System Administrator for Adaptive, ensuring the integrity of our planning tools Governance & Compliance: Advise internal stakeholders on corporate policies and compliance to ensure proper GAAP treatment of expenses throughout the organization. Requirements Education: Bachelor’s Degree required, Master's degree preferred. Experience: 15+ years of progressive financial management experience, 5+ years building and managing high-performing teams. Industry Expertise: Proven experience in the Biotech/Life Science industry, specifically R&D, Clinical Trial, and Commercial Planning. Systems and Tools: Proficiency with NetSuite, Coupa and Adaptive required. Communication: Strong verbal and written communication skills with previous experience supporting BoD level audiences. Leadership: Strong ability to lead through change and communicate complex financial concepts to diverse stakeholders. For candidates based in the SFB area, the salary range for this position is: $250,000 to $290,000. Benefits Comprehensive benefits package, including competitive employer premium contributions Meaningful stock option grants PTO, sick time, and holiday pay Generous Parental Leave program Pre-tax medical and dependent care programs STD, LTD, Life and AD&D Professional development opportunities Team-building events Fully stocked kitchen Fitness