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About Us   Kardigan is a heart health company working to make cardiovascular disease preventable, curable and no longer the leading cause of death in the world. It is Kardigan’s mission to develop multiple targeted treatments in parallel that bring people with cardiovascular diseases to the cures they deserve.   Led by Tassos Gianakakos, Jay Edelberg, M.D., Ph.D., and Bob McDowell, Ph.D., Kardigan’s co-founders have reunited after leading MyoKardia to discover and develop mavacamten, the first cardiac myosin inhibitor, resulting in an acquisition by Bristol Myers Squibb in 2020.   We have a cutting-edge discovery and translational research platform, a pipeline of late-stage candidates, and an industry-leading team that is driven to improve the lives of patients.   At Kardigan, we are motivated by our values which guide how we work, interact, and achieve our goals. Driven by patients and their families , we are deeply committed to improving the lives of patients and prioritizing their needs above all else. We believe in being authentic —leading with truth to bring out the best in others by creating an environment where every person knows they will be fully accepted. With an eagerness to learn , we encourage the highest levels of curiosity and are open to changing our minds. We are committed to winning as a team with urgency, excellence, and intention, and support each other no matter what role we play or where we sit. Lastly, we strive to enable the impossible because patients are counting on us. We are not afraid to take risks to unlock innovation and advance scientific discoveries.   These values are the foundation of our work, empowering us to make a real difference, every day.     Position Title:  Senior  Director, Clinical Lead   Department:   Program Management   Reports To:  Vice President, Global Program Head Location: Princeton, NJ or South San Francisco, CA – On-site 4 days per week (Mon to Thurs)       Job Overview   The Senior Director, Clinical Lead will be expected to lead to the clinical strategy, planning and execution for key aspects of clinical development of the program. Direct responsibilities include working with Global project team to identify the best clinical study that will provide the target product profile that was developed, planning and executing all activities related to the clinical trials of the program and that may also include other activities such as publication of study results and presentations.       Essential Duties and Responsibilities   Leads Clinical activities and is a key member of the Global Project Team.   In charge of strategy and planning clinical development of phase 1 to phase 3 and post launch study protocols, amendments, and other clinical research related documents and study reports   Provide clinical/scientific knowledge into the development, design, delivery, and communication of the global evidence generation plan   Support cross-functional and global collaborations to integrate broad medical, scientific, and commercial input into the development program   Interpret and communicate clinical trial data   Takes primary responsibility, working with statisticians, modelers, and project team-members, for study data analysis and interpretation, reporting and communication   Assists and provides oversight with the operational aspects of study conduct including site selection and activation, site investigator and staff training, budget planning and contract review   Leads the clinical part of the submission dossier in regulatory filings dossiers, and updates, regulatory briefing documents, Investigational Brochures, and other relevant documentation   Leads the clin