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Senior/Clinical Trial Manager (CTM)

Vor Bio
CompanyVor Bio
CategoryHealthcare
LocationBoston
RemoteOn-site (inferred)
EmploymentNot stated
LevelManager
SalaryNot stated by the employer
Posted23 Jul 2026
Last verified11 Aug 2026
SourceEmployer ATS (greenhouse)
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Description
J oin Us in Tackling Autoimmune Disease at Its Root At Vor, we believe science can do more than manage symptoms. It can change the course of disease. By advancing telitacicept, a first- and potentially best-in-class dual BAFF/APRIL inhibitor, we are silencing upstream survival signals and stopping downstream autoimmune cascades. Together, we are addressing disease at its root cause and rewriting what is possible for patients worldwide. When you join Vor, you’re not just working on a medicine. You’re part of a mission to redefine the future of autoimmune care. Why Work at Vor? Impact: Contribute directly to a medicine with best-in-disease Phase 3 results in myasthenia gravis and expansion into multiple autoimmune diseases. Growth: Be part of a rapidly scaling company with opportunities to grow your career in science, clinical development, commercial strategy, and beyond. Innovation: Work on a platform with potential beyond one indication — a therapy that has already shown consistent results across lupus, IgA nephropathy, and Sjögren’s syndrome. Belonging: Join a culture where every voice is heard, and where our shared mission unites us across functions and geographies.     Who we are looking for:   Vor Biopharma is seeking a Clinical Trial Manager/Sr. Clinical Trial Manager who will be responsible for leading all aspects of clinical trial management from study start through study closure.  Key areas of responsibilities:   Manage all clinical aspects of a clinical trial and ensures trial execution in compliance with ICH/GCP guidelines/regulations and applicable SOPs  Lead and collaborate effectively with cross-functional teams to oversee the setup, execution, and management of Vor Biopharma complex clinical trials according to plan and in the highest quality standards  Can multi-task in a fast-paced environment with changing priorities and maintain accurate forecasts, clinical trial budgets, and timelines  Assist in development and management of study budget and maintains it within financial goals; reviews and approves clinical invoices against approved budget  Use operational and therapeutic expertise to optimize trial setup, implementation, and execution   Proactively anticipate/identify study risks and issues, determine escalation pathway, and develop and implements solutions    Conduct project risk analysis and develops risk mitigation strategies for a variety of complex problems to maintain study deliverables  Provide technical expertise to oversee the development of clinical documents (protocol, informed consent form, CRF, monitoring plans, regulatory submission documents, clinical study report, investigator brochures, etc.  Provide clinical operations expertise and strategic leadership in the evaluation, selection, and management of CROs and other external vendors to ensure successful clinical trial implementation and execution of Vor Biopharma clinical trials and ensure that performance expectations are met  Provide expertise in the identification, engagement, and selection of key trial centers/PIs, as well as develop relationships with investigators and site staff  Ensure audit-ready condition of clinical trial documentation and support inspection readiness activities  Participate in the planning of quality assurance activities and coordinate resolution of audit findings, which includes management through resolution (CAPA) of any site or study level issues, deviations, etc.  Actively provide direction and oversight and foster effective relations