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Company Overview: Dyne Therapeutics is focused on delivering functional improvement for people living with genetically driven neuromuscular diseases. We are developing therapeutics that target muscle and the central nervous system (CNS) to address the root cause of disease. The company is advancing clinical programs for Duchenne muscular dystrophy (DMD) and myotonic dystrophy type 1 (DM1) as well as a preclinical programs for facioscapulohumeral muscular dystrophy (FSHD) and Pompe disease. At Dyne, we are on a mission to deliver functional improvement for individuals, families and communities. Learn more at https://www.dyne-tx.com/ , and follow us on X , LinkedIn  and Facebook . Role Summary   The Director, US Commercial Enablement drives strategic commercial enablement initiatives and builds foundational tools, processes, and capabilities to support business growth and launch readiness. The Director establishes and optimizes field enablement infrastructure, including incentive compensation, CRM platforms, and business intelligence tools, while ensuring alignment across cross-functional stakeholders. This role enhances field effectiveness, builds scalable processes, and promotes operational excellence with a patient-first mindset.   This position is based in Waltham, MA    Primary Responsibilities Include:   Incentive Compensation and Performance Programs   Leads planning, design, and administration of incentive compensation and bonus programs across commercial, medical, and patient services teams   Develops plan design models, manages payouts, and delivers monthly and quarterly reporting   Maintains plan documentation, tracking systems, and performance monitoring processes   Conducts regular performance reviews with stakeholders to optimize program effectiveness   Partners with field teams to build account planning tools   Leads recognition programs, including Circle of Excellence and associated planning   Commercial Systems, Tools, and Analytics   Serves as commercial business owner for CRM platforms (e.g., Veeva), translating field needs into system enhancements   Partners with IT and stakeholders to implement and optimize CRM and data solutions   Owns business intelligence reporting tools and ensures data accuracy through quality control processes   Supports reporting platforms across market access and patient services   Optimizes field enablement tools and materials to improve productivity and effectiveness   Field Operations and Infrastructure   Designs and implements fleet program aligned with business needs and industry benchmarks   Maintains and updates fleet policies in collaboration with Compliance, HR, Finance, and Field Leadership   Builds scalable processes to support field teams and commercial operations   Cross-Functional Planning and Execution   Leads coordination of national, regional, and headquarters meetings in partnership with Marketing and Commercial teams   Drives cross-functional planning across Sales, Marketing, Market Access, Advanced Analytics, Patient Services, Finance, and IT   Ensures alignment and readiness to support commercial launch and execution   Strengthens collaboration and communication across teams   Education and Skills Requirements:   Bachelor’s degree; advanced degree preferred   12+ years of experience in biotech, pharmaceutical, or life sciences industry, including field sales, sales leadership, field operations, or consulting experience supporting commercial organizations   Demonstrated experience supporting or leading launch readiness, ideally in rare disease, neuromuscular