Job Opportunities API

At AstraZeneca, we push the boundaries of science to deliver life-changing medicines. Our global Safety Sciences organization delivers innovative non-clinical safety science and toxicology   expertise   to enable the discovery,   development   and registration of novel medicines. We are   seeking   a highly motivated   Director, Project Toxicologist ,   to join our   Safety Sciences China   group.   This role will   bring non-clinical safety   expertise   and effective   discovery and regulatory   toxicology strategies to   deliver   new candidate drug   project s   (internally and/or with collaborators),   ensuring   local   preclinical safety input that integrates seamlessly into global development and submissions . You   will   partner with   global   cross-functional teams across   therapeutic areas   and modalities   (small molecules, radio - conjugates,   immune-cell engagers,   antibody–drug conjugates,   peptides,   etc ) . Job description • Lead regulatory and investigative toxicology study design, developing strategies to predict, assess, and mitigate target- and modality-related safety risks. • Apply your toxicology expertise to predict clinical safety risks and , as   core member of drug project teams,   support data-driven decisions across discovery and development programs. • Provide strategic toxicology input for in-licensing evaluations and external collaborations. • Communicate integrated risk assessments to governance bodies and contribute to regulatory submissions. • Maintain and expand   expertise   in regulatory standards, preclinical safety, and modality-specific safety science, staying ahead of industry trends. • Innovate at the intersection of regulatory toxicology and   cutting-edge   science,   leveraging   in vitro, in silico, in vivo, and emerging technologies like organ-on-chip, imaging, and omics , and c ontribute to internal and external scientific reputation   through internal and external collaborations, publications, and thought leadership . • R ole model demonstration of AZ Values. Essential skills and experience • PhD and/or DABT in Toxicology, Pharmacology,   Cell Biology,   Pathology   or related field ,   with a strong scientific   track record   (or another university degree with   relevant work experience) . • Robust   experience in Project Toxicology, Investigative Toxicology, or related   non-clinical   safety-focused roles in pharma, biotech, or CRO environments. • Deep understanding of drug discovery and development, with proven ability to deliver toxicology programs supporting IND filings. • Expertise   across small and large molecule modalities   and relevant therapeutic areas ( e.g.   Oncology , Cardiovascular, Metabolism, Immunology, Respiratory). • Excellent communication, interpersonal, and influencing skills to inform decisions across scientific and regulatory teams.   Fluency in English and Mandarin is essential. Strong awareness of work-related cultural aspects across China, EU, UK,   US   and a proven ability to work across geographies and cultural barriers, building trust and effective collaboration in a global pharma environment. • Skilled in   using in   vitro, in silico, and in vivo tools to predict clinical safety risks. • Collaborative, problem-solving mindset with the ability to coordinate   and prioritize   across multiple projects . Date Posted 04-6月-2026 Closing Date AstraZeneca embraces diversity and equality of opportunity.  We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills.  We believe that the more inclusive we are, the better our work will be.  We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics.  We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.