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Company Overview Immunome is a clinical-stage targeted oncology company committed to developing first-in-class and best-in-class targeted cancer therapies. We are advancing an innovative portfolio of therapeutics, supported by a leadership team with deep experience in the design, development, and commercialization of cutting-edge therapies, including antibody-drug conjugates. Our pipeline includes varegacestat, an investigational gamma secretase inhibitor for which an NDA has been submitted to the U.S. FDA; IM-1021, a clinical-stage ROR1 ADC; IM-3050, an IND-cleared FAP-targeted radiotherapy; and IM-1617, an IND-cleared solid tumor ADC. We are also advancing a broad portfolio of early-stage ADCs pursuing undisclosed solid tumor targets. Position Overview The Associate Director / Director, Total Rewards will strengthen engagement and retention by building a competitive, scalable, and employee-centered total rewards. This role will lead the design and administration of compensation practices, benefits, leave programs, 401(k), equity planning, and rewards & recognition ensuring our offerings attract, motivate, and retain top talent while remaining compliant, cost-effective, and aligned to our culture.    Responsibilities Engagement and Retention   Develop and execute a total rewards strategy that supports talent attraction, engagement, and retention.    Partner with other functions of HR and business leaders to ensure rewards programs reinforce performance, internal equity, and our culture.    Translate company growth and workforce needs into scalable and fiscally responsible rewards programs .           Compensation Programs   Lead the development, implementation, and ongoing management of compensation plans, including salary structures, incentive programs, market pricing, pay equity analysis, and compliance oversight.    Support equity planning (new hire grants, promotions, refresh cycles, and annual planning) in coordination with Finance, Legal, and the equity administration partner.    Prepare for and support the annual compensation cycle (merit, promotion, bonus planning as applicable): tools, timelines, manager guidance, calibration support, and reporting.    Assist Chief Financial Officer by researching trends, gathering  data  and preparing compensation information to be reviewed by executive team, compensation committee, and board of directors.        Benefits Administration     Oversee day-to-day  benefits  administration including medical, dental, vision, life/AD&D, disability, FSA, and related programs.    Own leave administration processes (e.g., FMLA, state leaves, disability coordination), ensuring  an excellent  employee experience and compliant practices.    Manage 401(k) administration: vendor partnership, annual testing support, audits as needed, enrollment and education initiatives.    Lead annual benefits renewal: plan design evaluation, cost modeling, vendor negotiations, open enrollment project management, and employee communications.    Ensure compliance with applicable regulations (e.g., ERISA, COBRA, HIPAA, ACA) in partnership with legal/benefits vendors and internal stakeholders.        Rewards & Recognition     Own and improve recognition programs that reinforce values and performance (spot awards, peer recognition, and milestone/service awards).    Partner with people leaders to ensure recognition is  timely , inclusive, and consistently applied across teams.  &n