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Job Description: Company Overview Founded over a decade ago, CRISPR Therapeutics is a leading biopharmaceutical company focused on developing transformative gene-based medicines for serious human diseases. The Company has evolved from a pioneering research-stage organization into an industry leader, marking a historic milestone with the approval of CASGEVY ®  (exagamglogene autotemcel [exa-cel]), the world’s first CRISPR-based therapy, approved for eligible patients with sickle cell disease and transfusion-dependent beta thalassemia. CRISPR Therapeutics is advancing a broad and diversified pipeline across hemoglobinopathies, cardiovascular, autoimmune, oncology, regenerative medicine and rare diseases. The Company continues to expand its leadership in gene editing through the development of SyNTase™ editing, a novel and proprietary gene-editing platform designed to enable precise, efficient, and scalable gene correction. To accelerate and expand its impact, CRISPR Therapeutics has established strategic collaborations with leading biopharmaceutical partners, including   Vertex Pharmaceuticals . CRISPR Therapeutics AG is headquartered in Zug,   Switzerland , with its wholly-owned U.S. subsidiary, CRISPR Therapeutics, Inc., and R&D operations based in Boston, Massachusetts and San Francisco,   California . Position Summary CRISPR Therapeutics is searching for an Associate Director, Clinical Scientist to provide scientific input for early and late stage clinical development programs. Responsibilities • Contribute to the scientific development of clinical studies in alignment with the clinical development plan, including authoring and reviewing clinical documents (e.g., protocols, investigator brochures, CRFs, ICFs, CSRs) • Perform initial review of clinical trial data (safety and efficacy), including assessing for consistency and completeness and providing preliminary assessments and recommendations • Significantly contribute to the oversight of the clinical study in collaboration with the clinical development lead • Present data and information to investigators and internal stakeholders, contributing to meetings with governance bodies and regulatory authorities • Collaborate with internal stakeholders (clinical operations, data management, clinical pharmacology, statistics, safety, commercial, and regulatory affairs) to ensure translation of the clinical protocol into operational deliverables • Collaborate with external stakeholders (CROs, investigators and clinical coordinators) to clarify data submissions • Support study execution as the scientific subject matter expert • Review and synthesize scientific literature and competitive intelligence to support study and program strategy • Develop scientific and protocol training presentations to support internal and external meetings; e.g., site qualification and initiation, investigator meetings, and training materials • Support preparation of scientific material for conference presentations or publications • Contribute to the authoring and revision of regulatory submissions • Perform analyses and generate scientific slide decks based on clinical, translational and other datasets • Provide mentorship to junior clinical scientists Minimum Qualifications • Advanced scientific or clinical degree (eg MD, PhD, PharmD, DNP, MSN , etc). with 8-12+ years of relevant experience in clinical or related research • Excellent oral and written communication skills and analytical skills • Deep expertise in clinical science, with a strong track record of contributing to clinical studies • Ability to work collaboratively in a fast-paced, team-based matrix environment • In-depth understanding of clinical development processes, regulatory requirements, and guidelines (FDA, EMEA, ICH, GCP) • Strong analytical and strategic thinking skills, experience with interacting with medical monitors, development operations (preclinical, clinical operations, regulatory affairs, Quality Assurance) and clinical investigators Preferred Qualifications • Experience in cellular therapies/CAR-T trials • Experience in Phase 1/Phase 2 clinical trials Competencies • Collaborative – Openness, one team, positivity • Undaunted – Fearless, can-do attitude, self-starter • Results Orientation – Delivering progress toward our mission; Sense of urgency in solving problems; Attention to details; Practical • Entrepreneurial Spirit – Proactive; Ownership mindset; Thinks outside the box CRISPR Therapeutics believes in fostering a dynamic workplace that balances remote work flexibility with the benefits of in-person interactions. Our employees work at least three days on-site, creating a collaborative work environment, where we cultivate mentorship opportunities, increase cross-functional communication and offer opportunities for our employees to connect. Certain lab based and manufacturing positions are located fully on-site. Associate Director, Clinical Scientist: Base pay range of $170,000 to $185,000+ bonus, equity and benefits The range provided is CRISPR Therapeutics’ reasonable estimate of the base compensation for this role. The actual amount will be based on job-related and non-discriminatory factors such as experience, training, skills, and abilities. CRISPR Therapeutics, Inc. is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, gender, age, religion, national origin, ancestry, disability, veteran status, genetic information, sexual orientation or any characteristic protected under applicable law. To view our Privacy Statement, please click the following link: http://www.crisprtx.com/about-us/privacy-policy