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Erasca is a clinical-stage precision oncology company focused on discovering, developing and commercializing medicines for the benefit of patients with cancer. Our programs take novel approaches to shutting down one of cancer’s  most commonly mutated signaling cascades, the RAS/MAPK pathway, which affects approximately 5.5 million lives each year worldwide. The name “Erasca” has an important embedded meaning: it is a contraction of our audacious hope to “erase cancer” that drives our mission and everything that we do on behalf of patients with cancer. Reporting to the Chief Medical Officer, the SVP Biometrics will be accountable for biometrics activities for all programs from IND-enabling to registration and launch. This includes leadership of the Biostatistics, Statistical Programming & Analysis, and Clinical Data Management functions. This role requires hands-on execution as well as oversight of internal and external staff. In addition, this person will represent the Biometrics function on the Erasca leadership team and in cross-functional discussions and decision making. The ideal candidate will have excellent technical skills, a track record of developing and mentoring strong teams, significant experience in all phases of oncology drug development, a track record of successful regulatory interactions, and excellent communication skills and executive presence.   Essential  D uties and  R e sponsibilities :   Build,  m aintain ,  and develop a high performing team across Biostatistics, Statistical Programming  & Analysis , and Clinical Data Management.   Ensure systems, capabilities and resources are in place that  optimize  the design, conduct,  analysis  and interpretation of clinical and nonclinical data for  all  program s .   Demonstrate technical excellence ,  delivering advanced biometric strategies across the portfolio.    Act as the subject matter expert for biometrics,  advising  senior management, development, and clinical operations teams on current biostatistics  methodology  and tools in drug development.   In collaboration with  VP , Biostatistics, ensure statistical analysis and submission datasets meet regulatory requirements.   In collaboration with VP, Statistical  Programming & Analysis, ensure the intended analyses are performed, and  analysis  data sets and their specifications are in place.   In collaboration with Sr Director, Clinical Data Management,  provide  support to clinical study teams on the collection,  interpretation  and reporting of clinical data.   Provide input on key development documents, clinical protocols, study reports, IBs, INDs, NDAs, and labeling for all products.   Support preparations for interactions with regulatory agencies and provide guidance to ensure high quality preparation of Regulatory Authority documents (clinical study reports, submissions, clinical protocols, safety reports, etc.). Represent biometrics in interactions with regulatory agencies and health authorities.   Review and comment on eCRFs, annotated eCRFs, edit checks documents, and other clinical data management related documents.   Stay abreast of emerging technologies and concepts related to applied statistical  methodology .   Lead biometrics due diligence in support of business and corporate development activities.   Establish and further embed  biometrics  SOPs, processes, and relevant quality management  system .   Ensure  appropriate resourcing  of the biometrics organization by&nb