Job Opportunities API

About the Role 10x Genomics is rewriting the rules of biological discovery — and our platform needs to move as fast as our science. We are building a modern, AI-first technology stack, and this role sits at the center of it. We are looking for a Senior TPM who thrives in ambiguity, builds the plan rather than inherits one, and understands that data programs are not just delivery work — they are the foundation that makes AI possible. You will own the roadmap across our AI / Data Platform and integration programs, and you will expand your scope as the org scales. You have operated in environments where the process did not exist yet — and you built it. You do not wait for a fully-defined charter. You are energized by a flat org, a direct reporting line to leadership, and the expectation that you own outcomes end-to-end. What You Will Own Program Ownership & Delivery   Own and drive the roadmap across AI / Data Platform and Finance integration programs; expand scope as the business grows.   Take programs from zero to shipped — scoping, sequencing, dependency management, risk visibility, and retrospective.   Translate ambiguous business problems into structured, time-bound programs with clear milestones and decision points.   Run delivery end-to-end without needing a playbook handed to you. You write the playbook.   Hold engineering, product, and business teams accountable to commitments — without relying on hierarchy to do it. AI-First Thinking   Understand how Data Platform programs create upstream capability for AI and ML — design with that lens from day one.   Own AI-specific program tracks: NLQ rollout, Bedrock integrations, model deployment pipelines, and data readiness for AI.   Partner with Data Engineering, Product, and Science teams to ensure programs are not just delivered but compound into AI readiness.   Push teams to think end-to-end: what does this program unlock downstream, and are we building toward that?   Represent the AI program portfolio to senior leadership with clarity on status, risks, and strategic trajectory. Finance & Application Integrations   Own delivery of modernized integration programs — ensuring cross-application flows (ERP, CRM, supply chain) work reliably on a modern tech stack.   Drive the retirement of fragile legacy middleware and the adoption of event-driven, scalable integration patterns.   Partner with Finance, Operations, and Engineering to translate business process requirements into well-architected integration programs.   Ensure tax, order management, procurement, and revenue-impacting workflows have zero-tolerance reliability standards.   Define the integration roadmap in partnership with architects and engineering leads — own it, defend it, and ship it. Leadership & Communication   Operate effectively in a flat org: influence without hierarchy, build alignment without bureaucracy.   Be the connective tissue across Engineering, Product, Finance, and Operations — translate technical complexity into business impact.   Identify cross-program risks before they become incidents. Escalate with a proposed solution, not just a flag. Minimum Requirements   5 years of TPM experience with demonstrated ownership of complex, multi-stakeholder programs.   Meaningful time at a mid-stage startup (Series A–D), or equivalent experience as a founder or early employee — you know what it means to build without a safety net.   Hands-on delivery across data infrastructure or data platform programs: pipelines, warehousing, ELT, real-time data flows.   Fluency in modern integration patterns — you can hold a substantive conversation with engineers about event-driven architecture, API design, and middleware retirement without needing a glossary.   Proven ability to build