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InterSystems is a global leader in healthcare data management and interoperability, providing mission-critical technology that powers hospitals, health systems, and national infrastructures worldwide. Our products underpin trusted healthcare and financial systems where performance, availability, and security are non-negotiable. As a Senior Program Manager, you lead large-scale, complex, cross-functional initiatives across product, engineering, cloud, and AI. You operate across organizational boundaries, translating objectives aligned to corporate strategy into coordinated, measurable outcomes. You support and operationalize the security strategy across the portfolio, ensuring effective execution through structured programs. Security and performance are horizontal capabilities across our stack. You partner with product, engineering, and architecture to maintain consistent execution across the portfolio. Key Characteristics Thrives in high ambiguity, competing priorities Owns outcomes at a program level Connects strategy to execution (systems thinker) Influences without authority Execution-focused; manages complexity Communicates clearly across technical and business audiences Key Responsibilities Program Strategy, Execution & Delivery Execute against existing program direction and strategic priorities, incorporating security and performance, and influencing future prioritization and execution Translate program strategy into execution plans across multiple teams and projects Lead concurrent projects to deliver program objectives Coordinate execution with program managers across cloud, database, interoperability, HealthShare, and AI-enabled systems Align scope, priorities, and dependencies to enable delivery Cross-Functional Leadership & Stakeholder Management Orchestrate work across product, engineering, architecture, compliance, and operations Serve as integration point for dependencies, timelines, and deliverables Manage senior stakeholders, including executive engagement Communicate progress, risks, and decisions to support leadership action Run structured updates and program reviews to maintain alignment Program Performance, Health & Continuous Improvement Monitor program performance and health against established KPIs, objectives, and milestones; contribute to KPI refinement Manage risks, issues, and dependencies; escalate when needed Maintain clear program visibility and enforce accountability Improve execution, coordination, and operational effectiveness Qualifications Bachelor’s degree in Computer Science, Business, Engineering, or related field; advanced degree preferred 10+ years leading large-scale, complex, cross-functional programs Strong fundamentals in planning, scheduling, dependency and risk management Experience managing performance to KPIs and driving accountability Experience in cloud, healthcare, or enterprise technology environments preferred Proven ability to influence senior stakeholders without direct authority Strong communication and leadership skills PMP or equivalent certification a plus Experience using AI-assisted tools (e.g. copilots, summarisation tools, or chatbots) with an ability to critically evaluate and verify AI-generated outputs Demonstrated ability to learn, evaluate, adapt to, propose and implement AI-augmented workflows in order to continually enhance your own, and the team’s productivity We are an equal-opportunity employer and do not discriminate because of race, color, religion, sex, national origin, ancestry, marital status, veteran status, age, disability, sexual orientation or gender identity or expression or any other legally protected category. InterSystems is an E-Verify Employer in the United States. InterSystems is providing a current good faith estimate of the anticipated base salary range for this position depending on a variety of fa