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Vir Biotechnology, Inc. is a clinical-stage biopharmaceutical company focused on powering the immune system to transform lives by discovering and developing medicines for serious infectious diseases and cancer. Its clinical-stage portfolio includes programs for chronic hepatitis delta and multiple PRO-XTEN ® dual-masked T-cell engagers across validated targets in solid tumor indications. Vir Biotechnology also has a preclinical portfolio of programs across a range of infectious diseases and oncologic malignancies.  Vir Biotechnology has exclusive rights to the universal PRO-XTEN ®  masking platform for oncology and infectious disease. PRO-XTEN ®  is a trademark of Amunix Pharmaceuticals, Inc., a Sanofi company. We believe the success of our colleagues drives the success of our mission. We are committed to creating a company where everyone feels supported and encouraged to give their best. THE OPPORTUNITY Vir Biotechnology is seeking an experienced Program Manager to provide senior-level leadership for Development Program Teams, including our Hepatitis Delta program in Phase III and NDA/BLA-enabling activities. In this role, you will partner closely with the Program Executive to lead cross-functional matrix teams responsible for advancing Vir Biotechnology’s mid- to late-stage assets through commercialization and life-cycle management.  You bring deep pharmaceutical program management experience across the development lifecycle, along with a strong track record of leading cross-functional teams and fostering a culture of high performance, empowerment, and delivery. In this role, you are a confident, adaptable leader who communicates with clarity and respect, builds strong teams, and drives execution.  This role is based at our San Francisco headquarters, with an expectation of at least three days per week in the office.  WHAT YOU'LL DO Cross-Functional Leadership and Collaboration Partner with the Program Executive to lead the global Program Team and drive strategy and execution for assigned programs Partner with Clinical Development sub-team lead and other functional leaders to drive operational execution and integrate sub-team activities into the broader program strategy Drive matrix team performance, alignment, and communication through effective leadership and disciplined use of Vir Biotechnology’s tools, processes, and team norms Timelines and Scenario Planning Build, maintain, and govern integrated global cross-functional program timelines that highlight dependencies, milestones, deliverables, decision points, and critical path activities, including developing and supporting portfolio-level timelines as needed Partner with Regulatory Affairs, Biostatistics, Clinical Operations, Safety, Translational Medicine, and Commercial to develop and execute integrated development and registration strategies Ensure data integrity and accurate reporting across timelines and other team tools and processes to support informed decision-making and reliable inputs for annual budgets, reforecasts, and long-range planning Strategic Program Planning Define program milestones, decision points, inflection points, and deliverables in partnership with the Program Executive and senior leadership and develop scenario-based plans and decision trees Communicate with governance committees and functional leaders to address program needs, risks, resource requirements, and recommendations, and help teams navigate organizational decision-making effectively Identify and leverage interdependencies across short-, mid-, and long-term program plans, and advise teams on risks and opportunities to accelerate development Program Activity and Risk Management Lead effective meetings&n