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Manager, HR Operations

Jade Biosciences
CompanyJade Biosciences
CategoryHR & Recruiting
LocationBoston; Remote; San Francisco; Seattle
RemoteRemote
EmploymentNot stated
LevelManager
SalaryNot stated by the employer
Posted3 Jul 2026
Last verified30 Jul 2026
SourceEmployer career page (greenhouse)
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Description
About Jade Biosciences   Jade Biosciences is a clinical-stage biotechnology company focused on developing best-in-class therapies that address critical unmet needs in autoimmune diseases. Jade’s lead candidate, JADE101, targets the cytokine APRIL, and is currently being evaluated in a Phase 1 clinical trial for the treatment of immunoglobulin A nephropathy. Jade’s pipeline also includes JADE201, an afucosylated anti-BAFF-R monoclonal antibody, as well as JADE301, an undisclosed antibody candidate, both currently in preclinical development. Jade was launched based on assets licensed from Paragon Therapeutics, an antibody discovery engine founded by Fairmount. For more information, visit  JadeBiosciences.com  and follow the Company on  LinkedIn .   Role Overview   As a growing startup company, Jade is looking for a hands-on Manager, HR Operations to build scalable processes and partner with our teams to enable Jade’s great culture. The Manager, HR Operations will lead and optimize HR processes, systems, benefits administration, and employee lifecycle operations. This individual will lead the efficient delivery of HR services while ensuring streamlined and compliant processes and amazing employee experiences. The Manager, HR Operations will partner closely with Payroll, Finance, IT, and business leaders to support Jade’s teams and growth. Key Responsibilities   Benefits Administration Oversee administration of health and welfare benefits, retirement plans and leave programs Manage new hire, annual open enrollment and employee benefit communications Partner with brokers and vendors to ensure effective program administration Monitor benefits compliance, audits, and reporting requirements Support benefits strategy by analyzing utilization, trends, and costs Payroll & Employee Lifecycle Support Collaborate with Payroll to ensure accurate employee data and timely processing Oversee onboarding, offboarding, employee status changes, and record management Manage HR documentation and personnel file administration Ensure seamless end-to-end employee experiences   HR Operations Lead the day-to-day administration and execution of HR operations Develop, implement, and streamline HR processes, policies, and procedures Manage HR operational projects and initiatives from planning through implementation Ensure compliance with federal, state, and provincial employment laws and regulations in the US and Canada Maintain HR policies, procedures, and employee records in accordance with legal requirements Stay informed of employment law changes and recommend process updates as needed Partner with Legal and Finance on compliance-related initiatives HR Systems and Data Management Lead the administration of HR systems and ensure the accuracy, integrity, and security of employee data Manage system configurations, workflows, security roles, reporting, and integrations Lead HR systems enhancements and implementation projects Develop dashboards and reports to support decision making Partner with Payroll and IT to ensure seamless system functionality Qualifications   Bachelor’s degree and 5-8 years of HR experience with 3+ years of progressive benefits, HR systems, and compliance experience required Experience in startup, high-growth organizations required, biotechnology experience preferred Experience administering benefits, HR systems and HR processes in a fast paced, growing organization Experience supporting US multi-state employee populations required, experience supporting Canadian employees preferred Strong knowledge of HR operations, benefits administration, and employment law Advanced HR systems and technology expertise including experience with HRIS platforms such as Paylocity Strong analytical and project management skills Strong attention to detail and commitment to data accurac
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Manager, HR Operations — Jade Biosciences · Job Opportunities API