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At Alamar, we are passionate about enabling our customers to make scientific discoveries that translate into clinical outcomes and benefit patients. Our team is growing quickly as we develop innovative approaches to measure critical protein biomarkers from liquid samples that can enable the earliest possible detection of disease. We believe the next frontier in biology is enabled by measuring proteins at higher sensitivity in highly multiplexed assays at the push of a button, which is something only Alamar can do. As we build our team, we seek collaborative, driven, intellectually curious people committed to solving complex challenges. Our culture rewards accountability and cross functional teamwork because we believe this enables the kind of breakthrough thinking that will accelerate our mission. Position Summary The Human Resources Manager will serve as a key operational leader within the HR function, managing core HR programs and processes across the employee lifecycle. This role is highly hands‑on and partners closely with leadership, managers, and external vendors to ensure compliant, efficient, and employee‑focused HR operations in a dynamic biotech environment. The ideal candidate brings strong HR generalist experience, a high degree of professionalism, and the ability to balance day‑to‑day execution with continuous process improvement. Duties and Responsibilities HR Operations & Employee Lifecycle Manage day‑to‑day HR operations including onboarding, offboarding, employee records, and HRIS data integrity Serve as a primary point of contact for employee questions related to policies, benefits, and employment practices Ensure accurate and timely execution of employee changes (status changes, promotions, transfers, terminations) Compliance & Employee Relations Ensure compliance with federal, state (especially California), and local employment laws Support employee relations matters including investigations, performance issues, and corrective actions in partnership with the VP of HR Maintain and administer HR policies, ensuring alignment with evolving legal and business requirements Benefits & Leave Administration Support administration of health, welfare, and retirement programs (including coordination with brokers and vendors) Manage leaves of absence (FMLA, CFRA, PDL, ADA accommodations) and ensure consistent application of policies Performance & Talent Support Support performance management processes, including annual reviews, goal setting, and manager guidance Partner with Talent Acquisition on recruiting coordination, offer processes, and onboarding experience Contribute to employee engagement initiatives, training programs, and culture‑building efforts Payroll Administration Prepare, review, and process multi‑state payroll accurately and on schedule, ensuring compliance with federal and state wage and hour laws Partner with Payroll vendors and Finance to validate payroll changes, bonuses, equity‑related impacts, and off‑cycle payments Assist with payroll audits, reconciliations, and year‑end activities Serve as a key liaison for employee payroll inquiries and issue resolution Immigration & Global Mobility Manage the company’s immigration program, partnering with external counsel on visa strategy, filings, renewals, and compliance Support employees and managers through immigration processes including H‑1B, TN, O‑1, and green card sponsorship where applicable Maintain accurate immigration records and tracking to ensure compliance with U.S. immigration and employment eligibility requirements Advise leadership on immigration risks, timelines, and workforce planning implications Employee Engagement & Culture Support the design and execution of employee engagement initiatives, including onboarding prog