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About RTW Investments RTW Investments, LP (“RTW”) is a global, full life-cycle investment and innovation firm dedicated to solving the most challenging, unmet patient needs. We are focused on company building and identifying transformational and disruptive innovations across the biopharmaceutical and medical technologies sectors. Our investment philosophy combines a deep understanding of disease, biology, medicine, and technology with a comprehensive view of commercial opportunities and challenges. Our talented team brings hands-on expertise in targeted areas of innovation, dedicated to the diligent exploration and support of emerging breakthroughs in both industry and academia. Our mission is simple: we power breakthrough therapies that transform the lives of millions. RTW Investments – Recent Press   Overview RTW seeks a highly motivated Controller to join its experienced and collaborative finance team. Reporting to the Director of Finance and Operations, the Controller will play a central role in overseeing the day-to-day accounting, financial reporting, and operational infrastructure across the firm’s fund platform, with a high level of involvement / oversight with our audits. This is a high-visibility position with broad exposure to complex strategies and multiple fund structures, suited to a candidate who can balance hands-on execution with leadership, work both independently and collaboratively in a fast-paced environment, meet deadlines, and manage competing priorities. Key Responsibilities Oversee the month-end NAV close process across the firm’s fund platform, including hedge funds, a publicly listed fund, and private equity/royalty/co-investment vehicles, working closely with fund administrators and service providers to ensure timely and accurate completion of all deliverables. Review daily and monthly reconciliations prepared by the fund administrator and internal team (positions, cash, trades, P&L, and investor allocations) and resolve breaks in a timely manner. Manage the financial reporting and audit processes for all funds, including annual GAAP financial statements, interim reporting, and coordination with external auditors; oversee additional reporting obligations applicable to the publicly listed fund. Oversee booking, and ongoing monitoring of complex private investments—including royalty interests, private equity positions, structured instruments, and other illiquid holdings—in the firm’s portfolio accounting system. Coordinate with fund administrators to calculate and review management and incentive/performance fees in accordance with fund governing documents and side letter agreements. Substantiate investor capital balances through detailed review of administrator allocations and shadow allocations; respond to investor and consultant inquiries in coordination with the Investor Relations team. Lead the firm’s regulatory filing process, including Form PF, Form ADV, Annex IV, CIMA, 13F, 13H, and other filings as applicable; ensure underlying data is accurate and well-documented. Partner with the tax team to support tax compliance and reporting, including K-1s, 1099s, FBAR, and ad-hoc tax matters across multiple fund and entity structures. Design, implement, and continuously improve internal controls, accounting policies, and process documentation across the fund platform. Identify and lead process and systems improvements to enhance accuracy, efficiency, and scalability as the platform grows. Manage, mentor, and develop 1–2 direct reports, providing technical guidance and helping to build a high-performing team. Serve as a key point of contact for fund administrators, auditors, tax advisors, and other external service providers; manage service-provider performance and deliverables. Support ad-hoc projects across the firm, including new fund launches, onboarding of new strategies or vehicles, and other strategic initiatives.